Cohorting KPC+ Klebsiella pneumoniae (KPC-Kp)–Positive Patients—A Genomic Exposé of Cross-Colonization Hazards
نویسندگان
چکیده
منابع مشابه
KPC-producing Klebsiella pneumoniae, finally targeting Turkey
We report here the first identification of the worldwide spread of Klebsiella pneumoniae carbapenemase-2-producing and carbapenem-resistant K. pneumoniae clone ST258 in Turkey, a country where the distantly-related carbapenemase OXA-48 is known to be endemic. Worryingly, this isolate was also resistant to colistin, now considered to be the last-resort antibiotic for carbapenem-resistant isolates.
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Increased incidence of infections due to Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae (KPC-Kp) was noted among patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) at a single hospital. An epidemiologic investigation identified KPC-Kp and non-KPC-producing, extended-spectrum β-lactamase (ESBL)-producing Kp in cultures from 2 endoscopes. Genotypi...
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We examined contamination of healthcare worker (HCW) gown and gloves after caring for patients with Klebsiella pneumoniae carbapenemase (KPC)-producing and non-KPC-producing Klebsiella as a proxy for horizontal transmission. The rate of contamination with Klebsiella species is similar to that of contamination with methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococcus...
متن کاملManagement of infections due to KPC-producing Klebsiella pneumoniae
The emergence of the Klebsiella pneumoniae carbapenemases in K. pneumoniae and other Gram-negative bacteria, usually on a background of multidrug resistance, has led to difficult therapeutic choices. Among available antibiotics, tigecycline and the polymyxins are the most frequently active against these organisms in vitro. Optimal therapy of infections due to these bacteria may involve maximiza...
متن کاملEmergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland.
1 Plasmidic β-lactamases KPC in Gram-negative pathogens are of the highest clinical and 2 epidemiologic concern, conferring resistance to all β-lactams, including carbapenems [15, 3 18]. The main KPC producer is Klebsiella pneumoniae, but other species are being identified 4 as well [15]. Strains with KPCs spread rapidly and cause outbreaks; in hospitals on the east 5 coast of the USA and in Is...
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ژورنال
عنوان ژورنال: Infection Control & Hospital Epidemiology
سال: 2020
ISSN: 0899-823X,1559-6834
DOI: 10.1017/ice.2020.701